Important information about sildenafil
Sildenafil is a medicine used mainly to treat erectile dysfunction (ED) in adult men. It is also used at different doses and under specialist supervision to treat pulmonary arterial hypertension. (nhs.uk)
For erectile dysfunction, sildenafil helps increase blood flow to the penis when a man is sexually stimulated.
Sildenafil does not automatically cause an erection and sexual stimulation is required for it to work.
120 mg is above the maximum recommended Sildenafil dose for erectile dysfunction.
For ED, the usual recommended dose is 50 mg taken when needed, approximately one hour before sexual activity. Depending on effectiveness and side effects, the dose may be reduced to 25 mg or increased to 100 mg.
The maximum recommended dose is 100 mg once per day. (Medicines.org.uk)
Therefore, 120 mg should not be presented as a standard or recommended ED dose.
If someone has been supplied a product labelled “Sildenafil 120 mg”, they should check the product, dose and source with a pharmacist or doctor before taking it.
Sildenafil belongs to a group of medicines called PDE5 inhibitors.
It increases blood flow to the penis during sexual stimulation, helping a man achieve and maintain an erection.
Sildenafil does not increase sexual desire or libido.
The standard UK recommended dose is:
50 mg, taken approximately one hour before sexual activity.
Depending on effectiveness and tolerability, a healthcare professional may prescribe:
The maximum recommended dose is 100 mg once a day. (Medicines.org.uk)
Do not take more than prescribed.
Taking 120 mg or more does not necessarily produce a better erection and may increase the likelihood of side effects.
Sildenafil is normally taken approximately one hour before sexual activity.
It can take longer to work if taken after a large or high-fat meal. (nhs.uk)
Sexual stimulation is required for Sildenafil to work.
Do not take more than one dose in 24 hours. (nhs.uk)
Common side effects can include:
Most side effects are mild and temporary, but speak to a pharmacist or doctor if they are troublesome or do not go away. (nhs.uk)
Serious side effects are uncommon but can occur.
Seek urgent medical attention for:
A prolonged erection, known as priapism, requires urgent treatment because permanent damage can occur if it is not treated promptly. (nhs.uk)
Call 999 for chest pain, a severe allergic reaction, a seizure or other life-threatening symptoms.
Never take sildenafil with nitrate medicines.
This includes medicines used to treat angina and some other heart conditions.
Examples include:
Sildenafil can significantly increase the blood-pressure-lowering effects of nitrates and the combination can cause a dangerous fall in blood pressure. (Medicines.org.uk)
This also includes poppers containing amyl nitrite or related nitrate substances.
If you use nitrates, tell your doctor or pharmacist before taking Sildenafil.
Sildenafil may not be suitable for people with certain cardiovascular conditions.
Tell your doctor if you have:
A healthcare professional can determine whether sexual activity and sildenafil are appropriate for you. (nhs.uk)
Sildenafil can lower blood pressure.
Particular caution may be needed if you take:
People taking alpha-blockers may be advised to start sildenafil at a lower dose. (Medicines.org.uk)
Alcohol does not have the same absolute contraindication as nitrates, but drinking a large amount can make it more difficult to achieve an erection.
Large amounts of alcohol can also increase dizziness and other unwanted effects. (nhs.uk)
Avoid excessive alcohol when using sildenafil.
Avoid grapefruit and grapefruit juice while taking sildenafil because grapefruit can increase sildenafil exposure and may increase the likelihood of side effects. (nhs.uk)
Tell your doctor or pharmacist about every medicine, supplement and herbal product you take.
Important interactions can involve:
The HIV medicine ritonavir is particularly important. UK prescribing information states that sildenafil should not be used with ritonavir for ED at normal doses; if used under specialist direction, the dose must be substantially reduced. (Medicines.org.uk)
Never combine Sildenafil with another erectile-dysfunction medicine unless specifically instructed by a healthcare professional.
Sildenafil can cause dizziness and temporary visual disturbances.
If you experience dizziness, blurred vision or other visual changes, do not drive, cycle or operate machinery until the symptoms have completely gone. (nhs.uk)
Sildenafil for erectile dysfunction is a medicine intended for adult men.
There is therefore normally no reason for a man taking sildenafil for ED to have concerns about pregnancy or breastfeeding.
However, Sildenafil is also used for other medical conditions, including pulmonary hypertension, where treatment circumstances can be different.
Women who are prescribed Sildenafil for another medical condition should discuss pregnancy or breastfeeding with their doctor.
The NHS states that Sildenafil is not usually used during pregnancy or breastfeeding, although a specialist may sometimes recommend it when the potential benefits outweigh the risks. (nhs.uk)
Sildenafil may not be suitable for everyone.
Tell your doctor if you have:
Some people with severe kidney or liver impairment may need a lower starting dose. (Medicines.org.uk)
Taking more Sildenafil than prescribed can increase the risk of side effects.
Possible effects include:
Taking excessive amounts can be particularly dangerous when combined with nitrates, recreational drugs or certain other medicines.
If you have taken more sildenafil than recommended and feel unwell, contact NHS 111 or seek medical advice.
Call 999 if you experience chest pain, severe breathing difficulties, loss of consciousness, a seizure or another life-threatening reaction.
Sildenafil for erectile dysfunction is normally taken as required, rather than as a regular daily treatment.
If you do not take a planned dose, simply do not take extra sildenafil to compensate.
Never take more than one dose in 24 hours. (nhs.uk)
Sildenafil is a prescription medicine and should only be used by the person for whom it has been prescribed.
Do not give your Sildenafil to another person.
A medicine that is appropriate for one person may be unsafe for another, particularly if they take nitrates or have cardiovascular problems.
Is 120 mg of Sildenafil safe?
120 mg is above the UK recommended maximum dose for erectile dysfunction.
The maximum recommended dose for ED is 100 mg once per day. (Medicines.org.uk)
Anyone who has been advised to take 120 mg should discuss the dose with a doctor or pharmacist before taking it.
What is the normal Sildenafil dose?
The usual recommended starting dose for ED is 50 mg, taken approximately one hour before sexual activity. Depending on response and side effects, it may be reduced to 25 mg or increased to 100 mg. (Medicines.org.uk)
How often can Sildenafil be taken?
For erectile dysfunction, the maximum recommended frequency is once per day. (Medicines.org.uk)
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Does Sildenafil automatically cause an erection?
No. Sexual Stimulation is required for sildenafil to work.
Can I take Sildenafil with Viagra?
Viagra contains Sildenafil. Taking Viagra together with another sildenafil product would increase the total dose and should not be done.
Can I take Sildenafil with nitrates?
No.
Sildenafil must not be combined with nitrate medicines or nitrate-containing recreational products such as poppers because of the risk of a dangerous fall in blood pressure. (Medicines.org.uk)
Can I drink alcohol with sildenafil?
Avoid excessive alcohol. Large amounts of alcohol can make it harder to achieve an erection and may increase unwanted effects. (nhs.uk)
Can sildenafil cause a prolonged erection?
Yes, rarely.
An erection lasting more than 4 hours requires urgent medical treatment. (nhs.uk)
Can sildenafil affect eyesight?
Temporary visual changes can occur. Sudden loss of vision is rare but requires urgent medical attention. (nhs.uk)
Call 999 immediately if you experience:
For urgent but non-life-threatening concerns, contact NHS 111.
This website provides general educational and safety information about sildenafil.
It is not a substitute for advice from a doctor, pharmacist or other qualified healthcare professional.
For erectile dysfunction, the UK maximum recommended sildenafil dose is 100 mg once per day. A product labelled 120 mg should not be treated as a standard recommended dose. (Medicines.org.uk)
Never combine sildenafil with nitrate medicines or poppers.
If you have heart disease, take blood-pressure medication, have recently had a heart attack or stroke, or take other medicines, speak to a healthcare professional before using sildenafil.
In an emergency, call 999. For urgent but non-life-threatening medical advice in England, contact NHS 111.
Medical information should be reviewed regularly because prescribing guidance can change.
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